Strategies

Data multiplicity

A high degree of data multiplicity is important for good quality, especially for data sets intended for phasing. High multiplicity is often difficult to achieve at many synchrotrons because of the restricted geometry. One simple method to improve the data quality is not to collect a full circle but two half-circles and rotate the crystal by half the frame width before collecting the second half-circle. This way reflections become statistically more independent, improving the signal to noise ratio.