Pseudo-translation

From CCP4 wiki
Revision as of 09:31, 24 March 2012 by Kay (talk | contribs) (Created page with "* R-values of a structure with pseudo-translation are higher than usual, e.g. starting R values after molecular replacement could be 70-80%. == Solving the structure == # obt...")
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search
  • R-values of a structure with pseudo-translation are higher than usual, e.g. starting R values after molecular replacement could be 70-80%.

Solving the structure

  1. obtain the pseudo-translation vector (PST) from sfcheck/phenix.xtriage/molrep
  2. generate a model (2 molecules in 1 pdb file) consisting of one molecule at (0,0,0) and one shifted by the PST in the orientation you found by mol rep and run molecular replacement with that model (note: the molrep program does all of this internally)
  3. if that fails, reprocess the data in P1 and try step 2 in all possible spacegroups, including those with lower symmetry (like P1 itself)