Soaking with heavy atoms: Difference between revisions

Revision as of 15:02, 17 July 2009

Bart Hazes' collection of properties of heavy metals
"Towards a rational approach for heavy-atom derivative screening in protein crystallography" by Agniswamy et al, Acta Cryst D 64, 354
Michael Sawaya's Preparing a Useful Derivative
Artem Evdokimov's Iodination of protein crystals for fun and profit
Sugahara et al's Heavy-atom Database System (HATODAS) - a WWW-based tool designed to assist the heavy-atom derivatization of proteins.
http://www.sbg.bio.ic.ac.uk/had/ - good table of HA and pH ranges
http://sis.niaid.nih.gov/cgi-bin/heavyatom_reactivity.cgi - Heavy Atom Reactivity Table (original paper)

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 * Sugahara et al's Heavy-atom Database System ([http://hatodas.harima.riken.go.jp/ HATODAS]) - a WWW-based tool designed to assist the heavy-atom derivatization of proteins.
 * http://www.sbg.bio.ic.ac.uk/had/ - good table of HA  and pH ranges
+* http://sis.niaid.nih.gov/cgi-bin/heavyatom_reactivity.cgi - Heavy Atom Reactivity Table ([http://sis.niaid.nih.gov/pub_pdf/Agniswamy-et-al-2008.pdf original paper])
 Links to a variety of HA databases: http://www.shapirolab.org/lab-links/had.html
 References: [http://dx.doi.org/10.1107/S0907444903020584 Lott JS et al. (2003) Acta Cryst D Biol Crystallogr, Dec (Pt 12): 2242-6. Making the most of two crystals: structural analysis of a conserved hypothetical protein using native gel screening and SAD phasing.]