2GIF

Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism

The structure of AcrB was solved by molecular replacement, followed by many cycles of refinement and model building. The raw data are available at ftp://turn5.biologie.uni-konstanz.de/pub/datasets/ .

Reference: Seeger, M.A., Schiefner, A., Eicher, T., Verrey, F., Diederichs, K., Pos, K.M. (2006) Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism. Science 313: 1295-1298

The goal of this XDSwiki project is to run different versions of XDS (and other data reduction programs if anybody would contribute the data reductions!), and to compare internal R-factor statistics against R-factors of the refined model.

More to come soon!