Phase problem: Difference between revisions

Phase problem (edit)

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 A recent introduction into the principles of phase calculation with the help of experiments ([[experimental phasing]]; SIR/MIR/SIRAS/MIRAS/SAD/MAD) can be e.g. found in Taylor, G. (2003) The phase problem. Acta Cryst D59, 1881-1890 [http://journals.iucr.org/d/issues/2003/11/00/ba5050/index.html].
-The phase problem may also be solved with the positioning of a similar molecule in the correct orientation and location in the asymmetric unit of the (crystallized) unknown structure. This approach is called [[Molecular Replacement|molecular replacement]] (MR).
+The phase problem may also be solved with the positioning of a similar molecule in the correct orientation and location in the asymmetric unit of the (crystallized) unknown structure. This approach is called [[molecular replacement|Molecular Replacement]] (MR).
-The solution of the phase problem with the help of [[Direct Methods|direct methods]] was awarded with the Nobel Prize in 1985 ([http://www.iucr.org/people/nobel-prize]). In the context of macromolecular crystallography, this approach is used in substructure determination, and at very high resolution (beyond 1.2A).
+The solution of the phase problem with the help of [[direct methods|Direct Methods]] was awarded with the Nobel Prize in 1985 ([http://www.iucr.org/people/nobel-prize]). In the context of macromolecular crystallography, this approach is used in substructure determination, and at very high resolution (beyond 1.2A).