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Phase problem: Difference between revisions
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== [[direct methods|Direct Methods]] == | == [[direct methods|Direct Methods]] == | ||
The solution of the phase problem with the help of [[direct methods|Direct Methods]] was awarded with the Nobel Prize in 1985 ([http://www.iucr.org/people/nobel-prize]). In the context of macromolecular crystallography, this approach is used in substructure determination, and at very high resolution (beyond 1.2A). | The solution of the phase problem with the help of [[direct methods|Direct Methods]] was awarded with the Nobel Prize in 1985 ([http://www.iucr.org/people/nobel-prize]). For an example, see [[Solve a small-molecule structure]]. | ||
In the context of macromolecular crystallography, this approach is used in substructure determination, and at very high resolution (beyond 1.2A). See also [[SHELX C/D/E]]. | |||