Crystallization screens and methods: Difference between revisions

Crystallization screens and methods (edit)

1,090 bytes added , 14 February 2008

67

edits

@@ Line 4: / Line 4: @@
 The exact formulations and all information for how to make the PACT screen are available as supplementary material of the original article by Newman et al[http://scripts.iucr.org/cgi-bin/sendsupfiles?cy5025&file=cy5025sup1.pdf&mime=application/pdf] and are available under Open Access policy.
+== Qiagen(Nextal) vs Hampton screens ==
+Nextal Classics Suite is almost exactly the same as the Hampton Screen I and II (except that it's 96 conditions, whereas two Hampton Screens amount to 98; also, Nextal's screen is reorganized to bring closer the similar conditions for easier observation).  Nextal Classics II Suite is almost exact replica of Hampton's Index Screen (even numbering is identical).  One exception is the proprietary (!) Tacsimate in Hampton's Index, which in NExtal's screen is replaced (somewhat inappropriately) by sodium citrate.
+== What is Tacsimate? ==
+"Tacsimate contains 1.36 M Malonic acid, 0.25 M Ammonium citrate tribasic, 0.12 M Succinic acid, 0.3 M DL-Malic acid, 0.4 M Sodium acetate, 0.5 M Sodium formate, and 0.16 M Ammonium tartrate dibasic."
+[http://www.hamptonresearch.com/assets/products/attachments/0000000225-0000000670.pdf What is Tacsimate?] or go to the source
+Searching for silver bullets: An alternative strategy for crystallizing macromolecules. Alexander McPherson and Bob Cudney. Journal of Structural Biology 156 (2006) 387–406.